GENERAL CATALOGUE
BU224 hydrochloride
HY-101170 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-101170
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Catalog No: HY-101170
CAS No: 205437-64-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BU224 hydrochloride is a selective and high affinity imidazoline I2 receptor ligand, with a Ki of 2.1 nM. BU224 hydrochloride is sometimes used as an I2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing A?-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimers disease research.
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