GENERAL CATALOGUE
Butein
HY-16558 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-16558
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medchemexpress.com/Butein.html
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Catalog No: HY-16558
CAS No: 487-52-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 ?M for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 ?M for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator STAC .
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