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C-021 dihydrochloride
GENERAL CATALOGUE

C-021 dihydrochloride

HY-103364A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-103364A

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Catalog No: HY-103364A
CAS No: 1784252-84-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

C-021 dihydrochloride is a potent CC chemokine receptor-4 CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived 35S GTP?S from binding to the receptor with an IC50 of 18 nM.

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