C-CBL Mouse Monoclonal Antibody

Description

EnkiLife offers the C-CBL Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Monkey,Rabbit species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: CBL; CBL2; NSLL; C-CBL; RNF55. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:50-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.