C-Kit Mouse Monoclonal Antibody

Description

EnkiLife offers the C-Kit Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA application. Alternative Names of Immunogen: PBT; SCFR; C-Kit; CD117; KIT. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000 Background: C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Research Area: PI3K-Akt signaling pathway,Hippo signaling pathway