GENERAL CATALOGUE
C105SR
HY-157088 · 1 mg
MedChemExpress · Cat: HY-157088
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Catalog No: HY-157088
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
C105SR is a cyclophilin D CypD inhibitor targeting to peptidyl-prolylcis-trans isomerase PPIase . C105SR inhibits mitochondrial permeability transition opening mPTP with an IC 50 of 5 nM. C105SR inhibits hypoxia and reoxygenation inudced hepatocyte apoptosis and increases the level of calcium retention capacity CRC . C105SR exhibits hepaprotective effect in ischaemia-reperfusion injury IRI mouse model.
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