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C1s-IN-1 trihydrochloride
GENERAL CATALOGUE

C1s-IN-1 trihydrochloride

HY-W371165 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-W371165

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Catalog No: HY-W371165
CAS No: 1376162-36-5
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

C1s-IN-1 trihydrochloride Compound A1 is the selective inhibitor for C1s protease with the Ki of 5.8 ?M. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC50 of 85 ?M, inhibits the activation of classic pathway with an IC50 of 22 ?M. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the Ki of 51.2 ?M.

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