C3aR Rabbit Polyclonal Antibody

Description

EnkiLife offers the C3aR Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000 Background: C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues., Research Area: Neuroactive ligand-receptor interaction;Complement and coagulation cascades;