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C5aR1 antagonist 2
GENERAL CATALOGUE

C5aR1 antagonist 2

HY-163379 · 50 mg

MedChemExpress · Cat: HY-163379

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Catalog No: HY-163379
CAS No: 2365161-92-6
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

C5aR1 antagonist 2 Compound 6a is an orally active C5a receptor 1 C5aR1 antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases.

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