

HY-163379 · 50 mg
MedChemExpress · Cat: HY-163379
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medchemexpress.com/c5ar1-antagonist-2.htmlDescription
C5aR1 antagonist 2 Compound 6a is an orally active C5a receptor 1 C5aR1 antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases.







