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Cabozantinib
GENERAL CATALOGUE

Cabozantinib

HY-13016 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-13016

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Manufacturer product page

medchemexpress.com/Cabozantinib.html
Catalog No: HY-13016
CAS No: 849217-68-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively . Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis.

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