

HY-156961 · 1 mg
MedChemExpress · Cat: HY-156961
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medchemexpress.com/glpg3667.htmlDescription
Cadefrecitinib GLPG3667 is a reversible, ATP-competitive and orally active TYK2 inhibitor with an IC50 of 2.3 nM. Cadefrecitinib inhibits IFN?/pSTAT1, and the IC50 values in human peripheral blood mononuclear cell PBMC and whole blood assays are 70 nM and 623 nM, respectively. Cadefrecitinib has the potential for the study of inflammatory and autoimmune diseases.