Calpain 11 Rabbit Polyclonal Antibody

Description

EnkiLife offers the Calpain 11 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: CAPN11; Calpain-11; Calcium-activated neutral proteinase 11; CANP 11. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:10000 Background: Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008],catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,tissue specificity:Highest expression in testis.,