GENERAL CATALOGUE
Camidanlumab tesirine
HY-141599 · 1 mg
MedChemExpress · Cat: HY-141599
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medchemexpress.com/camidanlumab-tesirine.htmlCatalog No: HY-141599
CAS No: 1853239-04-9
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress
Description
Camidanlumab tesirine ADCT 301 is an ADC comprising HuMax-TAC, a human IgG1 mAb directed against human CD25, stochastically conjugated through a dipeptide cleavable linker to a pyrrolobenzodiazepine PBD dimer warhead. Camidanlumab tesirine has a drugAAasAasAaantibody ratio DAR of 2.3. Camidanlumab tesirine binds human CD25 with picomolar affinity. Camidanlumab tesirine has highly potent and selective cytotoxicity against a panel of CD25-expressing human lymphoma cell lines.
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