GENERAL CATALOGUE
Candidalysin
HY-P10408 · 1 mg
MedChemExpress · Cat: HY-P10408
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Catalog No: HY-P10408
CAS No: 1906866-53-2
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity
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