Cap-dependent endonuclease-IN-10

Description

Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease CEN . Not only can Cap-dependent endonuclease-IN-10 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo pharmacokinetic and in vivo pharmacodynamic properties, and better hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has the potential for the research of viral infections including influenza A, influenza B and influenza C extracted from patent WO2021129799A1, compound 1-1 .