BioMall
Brand Store/MedChemExpress/Capmatinib hydrochloride
Capmatinib hydrochloride
GENERAL CATALOGUE

Capmatinib hydrochloride

HY-13404B · 5 mg

MedChemExpress · Cat: HY-13404B

₹40 – ₹70 approx.This price excludes freight and taxes. Please RFQ to get the final price.

Reach 3+ verified distributors

Catalog No: HY-13404B
CAS No: 1029714-89-3
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

Capmatinib INC280; INCB28060 hydrochloride is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor IC50=0.13 nM . Capmatinib hydrochloride can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib hydrochloride potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib hydrochloride is largely metabolized by CYP3A4 and aldehyde oxidase.

More from MedChemExpress

2-Bromohexadecanoic acid
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HDAC-IN-84
HY-170379
Apoptosis