

HY-142688 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-142688
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medchemexpress.com/carboxylesterase-in-2.htmlDescription
Carboxylesterase-IN-2 compound 4u is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease.