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CARM1 degrader-2
GENERAL CATALOGUE

CARM1 degrader-2

HY-156153 · 50 mg

MedChemExpress · Cat: HY-156153

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Catalog No: HY-156153
CAS No: 3032785-06-8
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC CARM1 degrader-2 compound 3e is a degrader DC50=8.8 nM of co-activator associated argininemethyltransferase CARM1 . PROTAC CARM1 degrader-2 degrades CARM1 in a VHL- and proteasome-dependent manner. Thus, PROTAC CARM1 degrader-2 inhibits methylation of CARM1 substrates such as poly A -binding protein PABP1 and BGR1-associated factor BAF155 and inhibits breast cancer cell migration.

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