GENERAL CATALOGUE
CARM1-IN-1 hydrochloride
HY-12759A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12759A
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Manufacturer product page
medchemexpress.com/CARM1-IN-1-hydrochloride.htmlCatalog No: HY-12759A
CAS No: 2070018-31-2
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
CARM1-IN-1 compound 7g hydrochloride is a highly potent and selective inhibitor of CARM1 IC50=8.6 ?M, CARM1/PABP1 , with low inhibitory activity against PRMT1 and SET7 IC50 667 ?M. CARM1-IN-1 hydrochloride inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 hydrochloride also inhibits the promoter activity of prostate-specific antigen PSA without significant cytotoxicity.
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