

HY-161334 · 50 mg
MedChemExpress · Cat: HY-161334
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medchemexpress.com/carm1-in-4.htmlDescription
CARM1-IN-4 compound 11f is a potent CARM1 inhibitor with IC50s of 9 nM and 56 nM for CARM1 and PRMT1, respectively. CARM1-IN-4 displays significant anti-proliferative effects on colorectal cancer cell lines. CARM1-IN-4 effectively inhibits the methyltransferase activity of CARM1 and prevents methylation of downstream proteins. CARM1-IN-4 induces apoptosis and shows antitumor activity.







