Phospho-Casein Kinase Iγ1/2/3 (Tyr263) Rabbit Polyclonal Antibody

Description

EnkiLife offers the Phospho-Casein Kinase Iγ1/2/3 (Tyr263) Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 Background: This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer., Research Area: Hedgehog;