CASP-7 Mouse Monoclonal Antibody

Description

EnkiLife offers the CASP-7 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: MCH3; CMH-1; LICE2; CASP7; ICE-LAP3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Research Area: Apoptosis