Caspr (4V9) Rabbit Monoclonal Antibody

Description

EnkiLife offers the Caspr (4V9) Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,IF-P application. Alternative Names of Immunogen: Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:2000,IF-P 1:200-1:2000 Background: Contactin-associated protein 2 (Caspr2) is a type I transmembrane protein and member of the neurexin superfamily that mediates nervous system cell-cell interactions through the Neurexin IV-Caspr-Paranodin (NCP) complex. Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.