GENERAL CATALOGUE
CAY10404
HY-121537 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-121537
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medchemexpress.com/cay10404.htmlCatalog No: HY-121537
CAS No: 340267-36-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CAY10404 is a potent and selective cyclooxygenase-2 COX-2 inhibitor with an IC50 of 1 nM and a selectivity index SI; COX-1 IC50/COX-2 IC50 of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer NSCLC cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities.