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CB2 receptor agonist 8
GENERAL CATALOGUE

CB2 receptor agonist 8

HY-168338 · 50 mg

MedChemExpress · Cat: HY-168338

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Catalog No: HY-168338
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

CB2 receptor agonist 8 Compound 17 is an agonist for cannabinoid receptor 2 CB2 receptor . CB2 receptor agonist 8 exhibits cytotoxicity in cells U87, RPMI 8226, HL-60, and L929 with IC50s of 91.03, 16.29, 23.51 and 564.6 ?M, respectively. CB2 receptor agonist 8 activates caspase 3/7, increases the expressions of pro-apoptotic genes BAX, BAD, BIM and tumor suppressor genes p53, and induces apoptosis in U87. CB2 receptor agonist 8 inhibits the migration of U87.

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