GENERAL CATALOGUE
CBPD-409
HY-158113 · 1 mg
MedChemExpress · Cat: HY-158113
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medchemexpress.com/cbpd-409.html
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Catalog No: HY-158113
CAS No: 3037549-86-0
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
CBPD-409 is an orally active PROTAC degrader for CBP/p300, with DC50 of 0.2AAasAasAa0.4 nM. CBPD-409 exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP and 22Rv1, with IC50s of 1.2AAasAasAa2.0 nM. CBPD-409 exhibits antitumor efficacy Red: CBP inhibitor GNE049 HY-108435 ; Blue: CRBN/cullin 4A Thalidomide HY-14658 ; Black: Linker .
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