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CBT-295
GENERAL CATALOGUE

CBT-295

HY-169004 · 5 mg

MedChemExpress · Cat: HY-169004

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medchemexpress.com/cbt-295.html
Catalog No: HY-169004
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress

Description

CBT-295 is an orally active autotaxin ATX inhibitor. CBT-295 exhibits a significant reduction in inflammatory cytokines like TGF-?, TNF-? and IL-6 levels, also reduced bile duct proliferation marker CK-19 and lowered liver fibrosis. The reversal of liver fibrosis with CBT-295 led to a reduction in blood and brain ammonia levels. CBT-295 also reduced neuroinflammation induced by ammonia. CBT-295 is promising for research of liver cirrhosis and associated encephalopathy.

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