

HY-169004 · 5 mg
MedChemExpress · Cat: HY-169004
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medchemexpress.com/cbt-295.htmlDescription
CBT-295 is an orally active autotaxin ATX inhibitor. CBT-295 exhibits a significant reduction in inflammatory cytokines like TGF-?, TNF-? and IL-6 levels, also reduced bile duct proliferation marker CK-19 and lowered liver fibrosis. The reversal of liver fibrosis with CBT-295 led to a reduction in blood and brain ammonia levels. CBT-295 also reduced neuroinflammation induced by ammonia. CBT-295 is promising for research of liver cirrhosis and associated encephalopathy.







