CBX4 (10P4) Rabbit Monoclonal Antibody

Description

EnkiLife offers the CBX4 (10P4) Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,FC,IP,IF-P application. Alternative Names of Immunogen: CBX4; hPc2; NBP16; PC2;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50,IF-P 1:100-1:200 Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I (PubMed:12679040). Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131 (PubMed:22825850).