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CbzNH-PEG4-CH2COOH
GENERAL CATALOGUE

CbzNH-PEG4-CH2COOH

HY-W403327 · 50 mg

MedChemExpress · Cat: HY-W403327

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Catalog No: HY-W403327
CAS No: 1451362-51-8
Pack Size: 50 mg
Brand: MedChemExpress

Description

CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid CO2H group and a benzyl Cbz protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators e.g. HATU forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.

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