GENERAL CATALOGUE
CC-647
HY-173614 · 5 mg
MedChemExpress · Cat: HY-173614
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Catalog No: HY-173614
CAS No: 1061605-35-3
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
CC-647 is a molecular glue modulator targeting Cereblon CRBN E3 ubiquitin ligase. CC-647 promotes the interaction between CRBN and ZBTB16 as well as its oncogenic fusion protein RAR?-ZBTB16 with a DC50 of 103 nM . CC-647 is promising for research of ZBTB16-RAR?-associated acute promyelocytic leukemia APL .
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