CCL4/MIP1 beta (2H8) Rabbit Monoclonal Antibody

Description

EnkiLife offers the CCL4/MIP1 beta (2H8) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF,IP application. Alternative Names of Immunogen: ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1;MIP-1-beta;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:10000,ICC/IF 1:100-1:200,IP 1:50-1:100 Background: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1- beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.