GENERAL CATALOGUE
CCR4 antagonist 3
HY-147385 · 5 mg
MedChemExpress · Cat: HY-147385
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medchemexpress.com/ccr4-antagonist-3-1.htmlCatalog No: HY-147385
CAS No: 20880
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
CCR4 antagonist 3 is a potent chemokine receptor 4 CCR4 antagonist with an IC50 value of 1.7 ?M for 125I TARC thymus and activation regulated chemokine . CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine MDC to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC IC50 = 6.4 ?M .
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