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CCR6 inhibitor 1
GENERAL CATALOGUE

CCR6 inhibitor 1

HY-112701 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-112701

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Catalog No: HY-112701
CAS No: 2437547-04-9
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 IC50, 30000 nM, and CCR7 IC50, 9400 nM . CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.

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