GENERAL CATALOGUE
CCT128930
HY-13260 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-13260
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Catalog No: HY-13260
CAS No: 885499-61-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
CCT128930 is a ATP-competitive and selective inhibitor of AKT IC50=6 nM for AKT2 . CCT128930 has 28-fold selectivity over the closely related PKA kinase IC50=168 nM through the targeting of Met282 of AKT Met173 of PKA-AKT chimera , as well as 20-fold selectivity over p70S6K IC50=120 nM . Antitumor activity.
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