CD140a Mouse Monoclonal Antibody

Description

EnkiLife offers the CD140a Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA,FC application. Alternative Names of Immunogen: PDGFRA; PDGFR2; PDGFR-2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. Research Area: PI3K-Akt signaling pathway,Hippo signaling pathway