CD147 (8C17) Rabbit Monoclonal Antibody

Description

EnkiLife offers the CD147 (8C17) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF,IF-P application. Alternative Names of Immunogen: 5A11; 5F7; Basigin; Bsg; CD147; Collagenase stimulatory factor; EMMPRIN; M6 leukocyte activation antigen; Neurothelin; OK blood group antigen; TCSF; Tumor cell derived collagenase stimulatory factor;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,IF-P 1:50-1:200 Background: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857).