CD164 Rabbit Polyclonal Antibody

Description

EnkiLife offers the CD164 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: CD164; Sialomucin core protein 24; MUC-24; Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD antigen CD164. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 Background: Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008],function:This is a carcinoma-associated protein, probably a mucin.,PTM:Highly N- and O-glycosylated; contains sialic acid.,PTM:The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain.,similarity:Belongs to the CD164 family.,tissue specificity:Small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma., Research Area: Lysosome;