CD18 Mouse Monoclonal Antibody

Description

EnkiLife offers the CD18 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for ICC,ELISA application. Alternative Names of Immunogen: LAD; MF17; LCAMB; LFA-1; ITGB2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.