CD20 Mouse Monoclonal Antibody

Description

EnkiLife offers the CD20 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ICC,ELISA application. Alternative Names of Immunogen: B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.