CD220 Mouse Monoclonal Antibody

Description

EnkiLife offers the CD220 Mouse Monoclonal Antibody. This antibody reacts with Human, Mouse, Monkey species and is suitable for WB,ICC,ELISA,FC application. Alternative Names of Immunogen: INSR; HHF5. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. Research Area: PI3K-Akt signaling pathway,Hippo signaling pathway