CD27 Rabbit Monoclonal Antibody

Description

EnkiLife offers the CD27 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF,FC application. Alternative Names of Immunogen: T14; S152; Tp55; TNFRSF7; S152. LPFS2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:200-1:500,FC 1:100-1:500 Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]