CD42b (1R11) Rabbit Monoclonal Antibody

Description

EnkiLife offers the CD42b (1R11) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC application. Alternative Names of Immunogen: Antigen CD42b alpha; BDPLT1; BDPLT3; BSS; CD42b alpha; DBPLT3; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; GPIbA; VWDP;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2000-1:20000,IHC 1:100-1:200 Background: CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.