CD49E Mouse Monoclonal Antibody

Description

EnkiLife offers the CD49E Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ELISA,FC application. Alternative Names of Immunogen: ITGA5; FNRA; VLA-5; VLA5A. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. Research Area: PI3K-Akt signaling pathway