CD6 Rabbit Polyclonal Antibody

Description

EnkiLife offers the CD6 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: CD6; T-cell differentiation antigen CD6; T12; TP120; CD6. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 Background: This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],function:Involved in cell adhesion. Binds to CD166.,PTM:After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.,PTM:Contains intrachain disulfide bond(s).,similarity:Contains 3 SRCR domains.,tissue specificity:Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain., Research Area: Cell adhesion molecules (CAMs);