GENERAL CATALOGUE
CDDO-dhTFEA
HY-112671 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-112671
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Catalog No: HY-112671
CAS No: 1191265-33-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
CDDO-dhTFEA RTA dh404 is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-?B. CDDO-dhTFEA restores hypertension MAP , increases Nrf2 and expression of its target genes, attenuates activation of NF-?B and transforming growth factor-? pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease CKD rats.
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