GENERAL CATALOGUE
CDK-IN-18
HY-201330 · 50 mg
MedChemExpress · Cat: HY-201330
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Manufacturer product page
medchemexpress.com/cdk-in-18.htmlCatalog No: HY-201330
CAS No: 2531743-46-9
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
CDK-IN-18 Compound EX.161 is an orally active, brain-penetrant and selective inhibitor of CDK2, CDK4, and CDK6. CDK-IN-18 inhibits the activity of cyclin-CDK complexes, blocks phosphorylation of the retinoblastoma protein pRb , arresting the cell cycle transition from G1 to S phase. CDK-IN-18 is promising for research of cancers, such as breast cancer especially hormone receptor-positive, HER2-negative type , lung cancer, and colorectal cancer.
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