

HY-146253 · 50 mg
MedChemExpress · Cat: HY-146253
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medchemexpress.com/cdk1-2-4-in-1.htmlDescription
CDK1/2/4-IN-1 compound 3a is a potent CDK inhibitor with IC50 values of 1.47, 0.78 and 0.87 ?M for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates Bax, caspase-3, P53 levels and decreases Bcl-2 level. CDK1/2/4-IN-1 can be used for cancer research.







