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CDK1/2/4-IN-1
GENERAL CATALOGUE

CDK1/2/4-IN-1

HY-146253 · 50 mg

MedChemExpress · Cat: HY-146253

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Manufacturer product page

medchemexpress.com/cdk1-2-4-in-1.html
Catalog No: HY-146253
CAS No: 2414633-49-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

CDK1/2/4-IN-1 compound 3a is a potent CDK inhibitor with IC50 values of 1.47, 0.78 and 0.87 ?M for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates Bax, caspase-3, P53 levels and decreases Bcl-2 level. CDK1/2/4-IN-1 can be used for cancer research.

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