

HY-173124 · 50 mg
MedChemExpress · Cat: HY-173124
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Manufacturer product page
medchemexpress.com/cdk2-flt4-pdgfra-in-1.html
Description
CDK2/FLT4/PDGFRA-IN-1 Compound 4a is a potent inhibitor of CDK2/cyclin A, FLT4 VEGFR3 and PDGFRA, with IC50s of 1.672, 0.554, and 0.629 ?M, respectively. CDK2/FLT4/PDGFRA-IN-1 exhibits potent antiproliferative effects against cancer cells lung EBC-1, pancreatic ductal adenocarcinoma AsPC-1, colorectal HT-29 cells . CDK2/FLT4/PDGFRA-IN-1 can also induce apoptosis in cancer cells.







