GENERAL CATALOGUE
CDK6/PIM1-IN-1
HY-142696 · 50 mg
MedChemExpress · Cat: HY-142696
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Manufacturer product page
medchemexpress.com/cdk6-pim1-in-1.htmlCatalog No: HY-142696
CAS No: 2677026-14-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
CDK6/PIM1-IN-1 is a potent and balanced dual CDK6/PIM1 inhibitor with IC50 values of 39 and 88 nM, respectively. CDK6/PIM1-IN-1 inhibits CDK4 IC50=3.6 nM . CDK6/PIM1-IN-1 significantly inhibits acute myeloid leukemia AML cell proliferation, arrest cell cycle at the G1 phase, and promote cell apoptosis. CDK6/PIM1-IN-1 exhibits potent anti-AML activity.
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