GENERAL CATALOGUE
CDK8-IN-12
HY-148561 · 5 mg
MedChemExpress · Cat: HY-148561
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medchemexpress.com/cdk8-in-12.htmlCatalog No: HY-148561
CAS No: 2613307-67-6
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. CDK8-IN-12 has off-target kinase inhibition on GSK-3?, GSK-3?, PCK-? with Kis of 13 nM, 4 nM, 109 nM, respectively. CDK8-IN-12 shows potent anti-proliferative effects selectively on MV4-11 cell. CDK8-IN-12 is an anti-cancer agent.
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